All these effects are mediated by the interactions of opioids with members of the opioid receptor family. Opioid binding sites were first discovered in mammalian brain (Pert and Snyder 1973 ...

Donald Trump has imposed tariffs on Mexico, Canada, and China, citing the fentanyl crisis as a significant issue exacerbating ...

The regular use of agonists of the μ-opioid receptor for acute pain relief usually leads to tolerance, respiratory depression, constipation and importantly, abuse potential. Discontinuation of chronic ...

Hydrocodone is a mu-opioid (μ-opioid) receptor agonist, which means it activates the mu-opioid receptors. It can also bind with different opioid receptors at higher concentrations. By doing this ...

The company tested cebranopadol, a dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist, in a late-stage trial on patients who have undergone cosmetic ...

Having shown last week that its opioid alternative can reduce post-surgery pain, Tris Pharma is back with another slice of clinical data to show that the drug is less likely to be abused.