Hydrocodone is a mu-opioid (μ-opioid) receptor agonist, which means it activates the mu-opioid receptors. It can also bind with different opioid receptors at higher concentrations. By doing this ...

Donald Trump has imposed tariffs on Mexico, Canada, and China, citing the fentanyl crisis as a significant issue exacerbating ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

The regular use of agonists of the μ-opioid receptor for acute pain relief usually leads to tolerance, respiratory depression, constipation and importantly, abuse potential. Discontinuation of chronic ...

Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and ...

An interesting new property was observed for methadone, which is known to act at NMDA (N-methyl-D-aspartate) and μ-opioid receptors. In this study, methadone and its analogues seemed to be more ...

As more and more receptors are induced, the individual requires greater and greater amounts of opioids/narcotics to quench their neuro-biochemical demand. ANR is the only treatment that treats the ...

Federal officials approved a new type of pain drug designed to eliminate the risks of addiction and overdose associated with opioid​ medications like Vicodin and OxyContin.