and synthesizes a complementary strand of DNA (red). B) When DNA polymerase randomly incorporates a fluorescently labeled ddNTP base, synthesis terminates. This step produces a mixture of newly ...

Trends in Genetics 22, 46–55 (2006). Argueso, J. L. et al. Double-strand breaks associated with repetitive DNA can reshape the genome. Proceedings of the Naitonal Academy of Sciences 105 ...