When they read existing research on this topic, the team discovered that in early stages of the disease, microglia are not yet activated. At the early stages, they're mostly homeostatic ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small ...

Inflammation is triggered by the immune system and is part of the body's natural response to injuries or disease. However, abnormal inflammation has recently been established as a hallmark for ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small fragments called micronuclei produced by neuronal nuclei are released into ...

This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

The agreement will allow Enigma to use its PET imaging tracer PMI04 to visualize microglia activity in neurodegenerative ...

Ashvattha Therapeutics (“Ashvattha”), a clinical-stage company advancing a new class of nanomedicine therapeutics that traverse tissue barriers to selectively target and reprogram activated cells in ...

However, when exposed to nefarious stimuli, microglia transition from a resting elongated and ramified form to an activated amoeboid state, coupled with an overall enhanced pro-inflammatory phenotype.