We show here that Fas kills activated primary T cells efficiently in the ... Thus, Fas, TRAIL and TNF receptors can initiate cell death by two alternative pathways, one relying on caspase-8 ...

Together these proteins enable the host to recognize and clear pathogens and altered host cells. The complement proteins C3 and protease factor B have a central role in the activation pathways of ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

The EV do not seem to enter circulation but stay within the heart. Ultimately, this is an alternative garbage disposal pathway used by cells to get rid of dysfunctional and damaged mitochondria when ...