These chains are interconnected by disulfide bonds, resulting in a characteristic Y-shaped structure with a total molecular weight of approximately 150 kDa. Each antibody molecule possesses ...

The method for creating bispecific κλ bodies is simple: a production cell expresses a single heavy chain, alongside κ and λ light chains, which self-assemble into functional antibodies.

As part of the team in 2017 that mapped the structure of a human antibody that could potently block the Zika virus ... “Despite all the human tragedy, SARS-CoV-2 was a relatively simple target in ...

structure, and motion of selected epitopes,” said Bright. “Our unique platform enables accelerated and diversified discovery and optimization of highly efficacious therapeutic antibodies ...