Legumain, also known as asparaginyl endopeptidase, is a cysteine protease that plays a significant role in various biological processes and has been implicated in the development and progression ...

FIH, on the other hand, hydroxylates an asparaginyl residue in the carboxy-terminal activation domain, which blocks p300 co-activator recruitment and results in the inactivation of HIF1α-subunit ...