Activation of TLR4 in airway fibroblasts by citrullinated vimentin leads to a pro-invasive, pro-fibrogenic phenotype, with subsequent airway remodeling and COPD. Aim 1: Determine whether PAD2 and ...

new data concerning the inflammatory and functional involvement of small airways in rhinitic patients without clinical asthma, together with further explorations of remodeling phenomena ...

Daclizumab was associated with reduced daytime asthma symptom scores (p = 0.018 ... with disease severity and may influence chronic airway remodeling. [196] IL-23, a member of the IL-12 family ...

These are symptoms that are attached to asthma, which is a surprisingly common condition. According to the Asthma and Allergy ...

In contrast, brittle asthma is characterized by severe airway inflammation, hyperresponsiveness, and airway remodeling, often resulting in recurrent exacerbations despite intensive therapy.” ...