with subsequent airway remodeling and COPD. Aim 1: Determine whether PAD2 and citrullinated vimentin, present in lung macrophages, BAL, plasma and EBC of a cohort of smokers and nonsmoker subjects ...

This article provides an extensive review of the role of interleukins in asthma ... their modulation can alter airway inflammation, hyper-responsiveness and airway remodeling.

These are symptoms that are attached to asthma, which is a surprisingly common condition. According to the Asthma and Allergy ...

In contrast, brittle asthma is characterized by severe airway inflammation, hyperresponsiveness, and airway remodeling, often resulting in recurrent exacerbations despite intensive therapy.” ...

Daclizumab was associated with reduced daytime asthma symptom scores (p = 0.018 ... with disease severity and may influence chronic airway remodeling. [196] IL-23, a member of the IL-12 family ...