Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral ...

When individual tumor cells are isolated and used to grow artificial 3D cell clusters in the laboratory, referred to as organoids, the conventional approach produces only spherical-like structures.

We opened them up. Instead of closed cyst structures, these organoids have a surface with the right orientation and specific cell types resembling the regional intestinal topography. Moreover, they ...

The cells maintained the ability to develop into specialized cell types. The organoids thus mimic the original organ with its variety of cell types. This is essential for accurately studying how ...

Patient-derived induced pluripotent stem cell (iPSC) organoids have emerged as an innovative tool for disease modeling and drug evaluation. Growing evidence highlights the advantages of organoids ...

New study successfully made CTC-derived organoids from breast cancer patients' blood samples to investigate cell survival and ...

A research team has successfully utilized human respiratory organoids (mini-organs) to propagate human rhinovirus C (HRV-C), ...

Organoids are cell culture models that functionally resemble an organ. They have the potential to speed up drug development, improve understanding of disease treatment in diverse populations ...