The bank has since established more than 2,300 cancer cell lines and organoids — 3D clusters of cultured cells that mimic the complex behaviour of living organs — using tissue samples from ...

When individual tumor cells are isolated and used to grow artificial 3D cell clusters in the laboratory, referred to as organoids, the conventional approach produces only spherical-like structures.

The cells maintained the ability to develop into specialized cell types. The organoids thus mimic the original organ with its variety of cell types. This is essential for accurately studying how ...

We opened them up. Instead of closed cyst structures, these organoids have a surface with the right orientation and specific cell types resembling the regional intestinal topography. Moreover, they ...

Patient-derived induced pluripotent stem cell (iPSC) organoids have emerged as an innovative tool for disease modeling and drug evaluation. Growing evidence highlights the advantages of organoids ...

Instead of trying to establish cancer cell lines, they built a large-scale library of tongue cancer organoids (TCOs) from surgery samples of 28 patients. Organoids are three-dimensional tissue ...

Organoids are cell culture models that functionally resemble an organ. They have the potential to speed up drug development, improve understanding of disease treatment in diverse populations ...

Organoids are cell culture models that functionally resemble an organ. They have the potential to speed up drug development, improve understanding of disease treatment in diverse populations ...