1907— Adolf Windaus and his associate W. Vogt produce histamine synthetically by removing the carboxyl group from the amino acid histidine. 1910—Henry Dale and his colleagues at the Wellcome ...

Histamine plays an important role in healthy immune functioning and neurotransmitter signaling. However, when these naturally ...

Cysteinyl leukotrienes are established mediators of bronchial asthma and have agonist roles analogous to those of histamine in allergic rhinitis. We now know that the substance originally termed ...