Figure 1: Phenotypes of lin-4 and lin-14 mutants. Why was I so pessimistic about the prospect of lin-4 being the harbinger of a diverse class of regulatory molecules of broad importance?

Genome-wide inference of microRNA modulators identified a post-transcriptional regulatory network in GBM that was predictive of aberrant expression of GBM driver genes. MicroRNA modulators in the PCI ...

Victor Ambros and Gary Ruvkun won this year’s Physiology or Medicine award for the discovery of microRNA and its role in post-transcriptional gene regulation. Danielle is an Assistant Editor at The ...