"Interestingly, precisely this pathway of cGMP formation has long been known in biochemistry and medicine as a promoter of bone growth," says study leader Robert Feil. Genetic variants of the ...

A bone sarcoma is a kind of tumor—a growth of abnormal cells in the bones. When the tumor grows out of control and destroys nearby tissue or spreads to other parts of the body, it's called malignant.

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a ...