This first human study on the effect of a 5-HT 1A receptor agonist buspirone on acute thermal sensory and pain perception demonstrated that buspirone in a clinically relevant dose has no effect on ...

Background: Buspirone is a partial 5-HT 1A receptor agonist ... Methods: The effects of buspirone (30 mg p.o.) on thermal sensory and pain thresholds were investigated in twelve female volunteers ...