In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first FDA ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

A team of researchers from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has developed a ...

The workflow for editing human iPSCs via CRISPR-Cas9 targeted single-cell cloning can seem daunting. We've broken down the protocol into a quick, easy-to-understand format that will restore your ...

While single-cell CRISPR screens based on the WTA approach were limited to a few hundred perturbations, the targeted sequencing workflow presented here will allow genome-scale CRISPR screens.

To streamline and accelerate tool development, TMO has also integrated Gibson Assembly into its CRISPR workflows, making it easier to clone large DNA fragments efficiently. On December 20 ...

A new iPSC-derived cellular tool with built-in Cas9 expression enables high efficiency knockout screening for drug target identification and validation. Functional genomics screening that leverages ...

Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of ...

Zhi-Kun Li at the Chinese Academy of Sciences in Beijing and his colleagues used CRISPR to create the mice, using a novel approach to target genes that normally need to be inherited from both male ...

On multiple occasions, Kennedy has commented on the potential of CRISPR, a potent and powerful gene-editing tool, to disrupt DNA in unintended and unsafe ways. The nonprofit that RFK Jr. founded ...