For solid tumors and hematological malignancies, CAR-NK cell treatment is a novel kind of cancer immunotherapy. CAR-NK cells work by killing cancer cells in a CAR-dependent way. CAR-NK cells and ...
For the new therapy, these cells are derived from stem cells that originated from healthy adult donor tissue - called induced pluripotent stem cells (iPSCs) - to make therapeutic CAR-NK cells.
This pioneering treatment modifies a patient's T cells ... Rezvani and her colleagues can produce more than 100 doses of CAR-NK cells. After treating 37 patients with CD19+ B-cell malignancies ...
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An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well tolerated both as monotherapy and in combination with rituximab among patients with B-cell ...