A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a ...

这项发表于 Cell 的研究表明，YTHDF2 在 B 细胞恶性肿瘤的起始、进展和免疫逃避中发挥着关键的致癌作用。YTHDF2 的小分子抑制剂 CCI-38 与 CD19-CAR-T 细胞 ...

"Next, we are studying how to dynamically adapt these CAR T cells at the synapse level to make them more effective." "Tumors are very sophisticated. We need to adapt our tools to the biology of ...

While the first generation of CAR-T cells that have recently been approved in the US have proved to be highly effective, they are costly to make and administer. The CAR-T process involves several ...

Therapeutic CAR-NK cells produced from iPSCs address some of the key limitations of CAR-T cell therapies and could make cellular immunotherapy more accessible globally." ...

“Next, we are studying how to dynamically adapt these CAR T cells at the synapse level to make them more effective.” “Tumors are very sophisticated. We need to adapt our tools to the biology of the ...