A dopa decarboxylase inhibitor (DDCI), such as carbidopa or benserazide, is administered with levodopa to attenuate its peripheral conversion to dopamine, reduce nausea and increase central ...

Combining levodopa with a DDC inhibitor (DDCI), such as carbidopa or benserazide, greatly reduces the incidence of nausea and vomiting, increases the levodopa half-life from approximately 60 to 90 ...

Regional cerebral blood flow (rCBF) was measured with positron emission tomography before and after levodopa (in the presence of carbidopa). The rCBF response to levodopa in medial frontal gyrus ...

According to DelveInsight’s epidemiology model, the total diagnosed prevalent cases of Parkinson’s disease were approximately ...

Nourianz (istradefylline) is sometimes prescribed alongside carbidopa and levodopa. Although its exact mechanism of action is ...

The LXM.5 pilot study reveals an 80% bioavailability increase compared to competing products combining levodopa and carbidopa. The study additionally shows sustained and smooth levodopa levels in ...