Continuous manufacturing (CM) has become a contentious topic in the modern pharmaceutical lexicon, driven by divergent ...

Capto S ImpAct is a strong cation exchanger for the intermediate and polishing steps when purifying MAbs and a wide range of other biomolecules. Part of the established Capto platform of ...

Scientists at the Indian Institute of Technology Delhi recently created a new machine learning (ML)-based tool for process verification during process chromatography unit operations.

Multimodal chromatography is an advanced technique ... such as ubiquitin and IgG1 Fc, to multimodal cation exchange resins. A study utilized a biophysical technique combining diethyl pyrocarbonate ...

After a purification process composed of three forms of chromatography—affinity, cation exchange, and ion-exchange—Inan and his colleagues compared the performance of the biosimilar to the ...

Current efforts involve: (i) using a combination of computational modeling and ion-exchange chromatography approaches as a means for predicting the strength of cation-arene and anion-arene ...

They enriched for phosphopeptides using strong cation exchange chromatography followed by immobilized metal ion affinity chromatography or by using a TiO 2 resin. By pooling the fractions and ...