These differentiation factors exert such ... Simply put, the EMT process results in a 'transdifferentiation' of epithelial cells forming a highly organized, tightly connected sheet of cells ...

This is not cellular transdifferentiation.) Even after we accept that functional differentiation to an heterologous cell type has been convincingly demonstrated, several additional issues require ...

To meet this need, our research applies a variety of systems to manipulate cell identity, including reprogramming, directed differentiation, transdifferentiation, and mouse models. We use molecular ...

The perturbation to epigenetic regulation by mutations can initiate differentiation and/or transdifferentiation that are required for tumorigenesis. The onset of this phenotypic instability and the ...

After injury, ependymal cells displayed minimal activation and demonstrated no significant proliferation or cross-lineage differentiation ... efficiency of astrocyte transdifferentiation into ...