These differentiation factors exert such ... Simply put, the EMT process results in a 'transdifferentiation' of epithelial cells forming a highly organized, tightly connected sheet of cells ...

To meet this need, our research applies a variety of systems to manipulate cell identity, including reprogramming, directed differentiation, transdifferentiation, and mouse models. We use molecular ...

The perturbation to epigenetic regulation by mutations can initiate differentiation and/or transdifferentiation that are required for tumorigenesis. The onset of this phenotypic instability and the ...

After injury, ependymal cells displayed minimal activation and demonstrated no significant proliferation or cross-lineage differentiation ... efficiency of astrocyte transdifferentiation into ...