生物通首页 > 今日动态> 专题总汇> Cell:miRNA与疾病 前言:疾病往往是由于对生理和病理应激作出的异常或不适当的反应所致。在过去的10年里,大量的研究揭示了哪些microRNAs (miRNAs)参与调控了这些情况下的细胞行为。在3月16日的《细胞》(Cell)杂志上 ...
Contrary to their traditional role, microRNAs (miRNAs) contribute to an increase in translation during cell quiescence. This function may be exploited for microRNA-mediated regulation of protein ...
来自杜克大学医学中心、上海第二军医大学等处的研究人员在新研究中揭示了一个乳腺癌抑制microRNA对的确切功能和分子作用机制。这一研究成果或将促使研究人员开发出更有效防治晚期转移性乳腺癌的药物。相关论文发表在《自然细胞生物学》(Nature Cell Biology ...
Since then, aided by advances in molecular biology and sequencing, scientists have discovered thousands of microRNA genes in the human genome that orchestrate cell and tissue development and cell ...
In hematopoietic cells, miRNA levels are dynamically regulated during lineage differentiation and also during the course of the immune response. Mouse models have provided good evidence for miRNAs ...
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