撰文丨王聪编辑丨王多鱼排版丨水成文衰老(Aging)是一种内在的生物学过程,其特征是系统性变化逐渐损害生理完整性,并增加患年龄相关疾病的风险,最终导致死亡。衰老的标志包括细胞衰老、基因组不稳定、表观遗传改变、蛋白稳态丧失、干细胞耗竭、慢性炎症以及细胞 ...
衰老(Aging)是一种内在的生物学过程,其特征是系统性变化逐渐损害生理完整性,并增加患年龄相关疾病的风险,最终导致死亡。衰老的标志包括细胞衰老、基因组不稳定、表观遗传改变、蛋白稳态丧失、干细胞耗竭、慢性炎症以及细胞间通讯改变等。其中,细胞衰老(Ce ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Gut microbiota-derived phenylacetylglutamine accelerates aging by driving cellular senescence through mitochondrial ...
The targeting of telomeres offers promise for new cancer therapies, which can be aimed at disrupting the mechanisms that ...
A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science ...