Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support ... to determine macromolecular structure or detect perturbations upon ligand binding, or to screen compound ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

Thioxanthones are fascinating organic compounds that have found their way into many industrial and everyday applications. In the printing industry, for example, they help inks dry faster when exposed ...

Insilico Medicine (“Insilico”) announces that the team, with the support of its generative chemistry engine, has developed a ...