Excess cortisol secretion caused by an overactive hypothalamic–pituitary–adrenal (HPA) axis is detrimental to immune function, metabolism and blood pressure, but knowledge of the effect of ...

Furthermore, metabolic factors including insulin and obesity-related signals may play a role in the regulation of both enzymes involved in the steroidogenetic pathways, as well as in the ...

Objectives: To examine the relationships between exposure to workplace factors (night work, extended working hours, psychosocial work stress) and cortisol secretion, and to test whether workplace ...

The results of combined patch clamp and secretion studies suggest a model for ACTH-stimulated cortisol secretion wherein cAMP functions in a dual capacity as a second messenger to activate parallel ...