In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

Scientists uncover how the nucleolus, a tiny structure within cells, may control aging and lifespan, opening new ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

The research is published today (Feb. 11, 2025) in Molecular Cell. Transfer RNA (tRNA) works with messenger RNA (mRNA) to construct proteins by way of complementarity, meaning that a tRNA sequence ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

If we can learn how this protein controls RNA transfer between cells, we could potentially develop better targeted treatments ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

When Xiao Wang applied to faculty jobs, many of the institutions where she interviewed thought her research proposal - to ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.