Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This ...

Announcing a new publication for Acta Materia Medica journal. The binding affinity of aptamers to targets has a crucial role in the pharmaceutical and biosensing effects. Despite diverse ...

This schematic shows the secondary structure of two aptamers. The complex shapes formed by base pairing (black lines connecting G-C and A-T bases) allow aptamers to bind their targets with high ...

More information: June H. Tan et al, Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing, Nature Biotechnology (2025). DOI: 10.1038/s41587-025-02554-7 Journal ...