Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...

David Rueda, Imperial College London CRISPR relies on two primary components: a guide RNA (gRNA) of 17-24 nucleotides that finds the target sequence and the Cas nuclease that cuts at that precise ...

Early reports have demonstrated that CRISPR effectively excises integrated human immunodeficiency virus type 1 (HIV) from cells. 1,2 For Michele Lai from the University of Pisa, these studies raised ...