Our laboratory is dedicated to understanding the consequences of activation of these pathways and to using this information to develop mechanism-based therapeutic strategies. The laboratory is ...
Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue ...
offering a more precise and potentially less harmful treatment pathway. Traditional cancer treatments often target the activity ofspecific enzymes, like ERK (extracellular signal-regulated kinase ...