These include hypertension, hypokalemia and edema and are easily manageable with a selective mineralocorticoid antagonist, such as eplerenone, or low-dose corticosteroids. Currently, abiraterone ...

One such drug is abiraterone acetate, which is an irreversible and specific inhibitor of CYP17, a rate-limiting enzyme in androgen biosynthesis. In early trials, abiraterone acetate was highly ...