Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, ...
The cell can control a metabolic pathway by the presence or absence of a particular enzyme. The cell can also regulate the rate of reaction of key enzymes. Enzymes are able to bind to their ...
To achieve this goal, cells organize reactions into various enzyme-powered pathways.
We have investigated the prediction of protein interactions through the analysis of domain fusion to assess whether metabolic enzymes have a higher participation in gene-fusion events compared ...
It's useful to differentiate these enzyme tools into two groups: core metabolism and specialized metabolism. For enzymes involved in core metabolism, organisms tend to have enzymes evolved to high ...
Promiscuous activities are important because they provide opportunities for evolution of new enzymes and new metabolic pathways, both in nature and in the laboratory. The Copley lab is engaged in ...
A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ ...
metabolism and appetite. Gordon's team employed a series of bioinformatics and biochemical tools to identify the enzyme—fatty acid amide hydrolase (FAAH)—that is produced by the bacterial ...