Epistasis describes how gene interactions can affect phenotypes. Did you know that genes can mask each other's presence or combine to produce an entirely new trait? But what happens when two ...

Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are ...

Did you know that genes can mask and alter the effects of other genes? Could this process, called epistasis, be a key to understanding complex conditions like Alzheimer’s disease and diabetes?

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

More information: Alejandro Cisterna-Garcia et al, Genome-wide epistasis analysis reveals significant epistatic signals associated with Parkinson's disease risk, Brain (2024). DOI: 10.1093/brain ...