This primer covers a range of options which often require complementary equipment, such as syringe pumps, for efficient ionization. ESI is the most common form of ionization used for MS. 3 It employs ...

1. Some guidelines for methods to ionize samples: a. Electrospray Ionization (ESI): Samples ionized by ESI are introduced into the instrument in a solution of polar solvents via a spray at atmospheric ...

These ionization methods can tolerate impurities provided that the impurity peaks do not overlap the sample peaks. Samples may be either solid or liquid; however, highly volatile liquid samples will ...