高度近视在全球的患病率呈上升趋势，已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症，发病年龄比年龄相关性白内障更早，严重影响患者工作期间的生活质量。由于晶状体核通常较硬，HMC 的手术干预难度较大，因此深入了解其发病机制对开发潜在治疗方法至关重要。

【导读】雌激素受体阳性（ER+）乳腺癌约占病例的 70%。靶向雌激素的内分泌疗法是 ER+ 乳腺癌的一线疗法。然而，约有一半的患者会对这些疗法产生耐药性，从而导致生存率降低。

This may hint at what lies ahead as we navigate the (mostly erroneous) tendency to identify every cell death process in drug hepatotoxicity and other liver diseases as ferroptosis. DILI is broadly ...

A recent Nature Communications study identifies ferroptosis as a major cell death mechanism underlying COVID-19 lung disease. Study: Fatal COVID-19 pulmonary disease involves ferroptosis.

was present in a range of contexts where ferroptosis was occurring, including in aging brains and Huntington disease-affected ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

Alzheimer's disease could be slowed by aerobic exercise ... "Iron overload in the oligodendrocytes is an inducer of ferroptosis in aged brains," the researchers wrote. The researchers found ...

Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...