This may hint at what lies ahead as we navigate the (mostly erroneous) tendency to identify every cell death process in drug hepatotoxicity and other liver diseases as ferroptosis. DILI is broadly ...

Background and aims: Ferroptosis, a novel concept of programmed cell death proposed in 2012, in kidney disease, has garnered significant attention based on evidence of abnormal iron deposition and ...

A recent Nature Communications study identifies ferroptosis as a major cell death mechanism underlying COVID-19 lung disease. Study: Fatal COVID-19 pulmonary disease involves ferroptosis.

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

The newly discovered protective function of 7-DHC opens up exciting prospects for further improving the treatment of cancer and other diseases associated with ferroptosis. "It gives us new ...

They found in the FECD samples the presence of certain genes associated with the disease and followed the path by which these genes led to ferroptosis. They also found through experiments that ...