Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

Ask someone what they think of when they hear the phrase "bile acids," and you might get a few unpleasant answers. Ask Robert Quinn, assistant professor in Michigan State University's Department ...

How did you discover MCBAs? Bile acids were first described chemically in 1849, and Heinrich Wieland was awarded a Nobel Prize in 1927 for comprehensively describing their chemistry. This ...

Cholesterol is required for the formation of bile acids, which are needed for fat digestion. It is also used to make important hormones such as estrogen and progesterone and is involved in the ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

This has been made possible in the last few years by the cloning of a number of membrane transporters in hepatocytes and cholangiocytes that determine the formation of bile. [1] The discoveries ...