To accomplish this challenging feat, origins of replication are prepared for 'firing' exclusively in the G1 phase of the cell cycle. After S phase is complete, replication origins do not fire ...

leading to cell cycle arrest in the G1 phase. Further investigation into the role of CDK4/CDK6 in ESCC was conducted through CRISPR-mediated gene knockout experiments. The depletion of CDK4/CDK6 ...

The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...