As results indicated that the spinal antinociceptive effect of diazepam is mediated predominately by GABA A receptor isoforms ... selective benzodiazepine-site agonist, L-838,417.

But a study published last week (October 3) in Science Translational Medicine, which zeroed in on GABA receptor levels, finds no evidence that their abundance is any different between people with ...

Gabather’s mission is to introduce novel treatments for psychiatric diseases by developing a pipeline of drug candidates that target GABA A receptors with greater accuracy and fewer side effects.

Attachment to the specific binding site enhances the affinity of GABA for its receptor site on the same receptor complex. The pharmacodynamic consequences of benzodiazepine agonist actions include ...