Although the mechanisms are unclear, cells are known to pull in external DNA molecules under ... The more “tries” a gene has to enter a genome, the more likely it is to be retained—an idea backed by ...
Using heat shock as a model system, we are studying the mechanisms that govern genome-wide changes to transcription in response to stress. Post-transcriptional control of gene expression can occur ...
The FDA assertion that horizontal gene transfer does not occur between transgenic ... and with purified DNA demonstrate the existence of mechanisms that would make such an event possible.
All these steps are performed exploiting the molecular mechanism that also allows bacteria to transfer resistance genes among each other. In many instances, the amplification of the gene clusters ...
Publication topics include RNAi approaches, drug resistance, hematopoietic progenitor cell gene transfer ... siRNA & ribozymes), apoptosis; mechanisms and therapies, vaccine development ...
This proposed Research Topic will focus on all areas relating to HGT including the diversity of transferrable genetic elements, functions conveyed on those elements (e.g. antimicrobial resistance and ...
These two mechanisms seemed to function separately, each playing its own role in distinct stages of the gene regulation process. Perhaps that was a mistake. In a publication in the journal Cell ...
The advent of technologies that permit efficient gene transfer in human primary cells creates novel therapeutic perspectives. Based on the use of recombinant oncoretroviruses and lentiviruses, we are ...
The Dölen lab studies the synaptic and circuit mechanisms that enable social behaviors. We use a variety of techniques including whole cell patch clamp electrophysiology, viral mediated gene transfer, ...