The genetics behind the progression of myelodysplasia to secondary acute myeloid leukemia (sAML) is poorly understood. In this study, we profiled somatic mutations and their dynamics using next ...

Recent progress in the molecular genetics of acute myeloid leukemia (AML) has shown this disease to be more heterogeneous than previously realized. Recurrent cytogenetic and mutational changes in ...

Additional techniques that may be used to further classify the type of leukemia include flow cytometric immunophenotyping [2] and genetic analysis. †Multiplex FISH (M-FISH) is a whole-genome ...

Using genetic fine-mapping analysis ... cells more chance to develop mutations that could eventually lead to overt leukemia." The new insights about IKZF1 bring researchers one step closer ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived ...

People with Down's syndrome face a higher risk of developing Leukemia. Now researchers from the University of Copenhagen and Stanford University explain why, by identifying specific changes in ...

Conduct deep phenotyping of children with DS-ALL to identify the impact of DS-related phenotypes on leukemia susceptibility and outcomes. Findings from this study may lead to improved genetic testing ...

Wiedemann-Steiner syndrome (WSS) research reveals MLL protein's role in neurodevelopment and potential therapeutic avenues for treatment.

Scientists from Flinders University in Australia have made a surprising discovery about a recently identified type of genetic material called circular RNAs. Their research suggests that these ...

A person’s lifetime risk of cancer might be partly established before they are even born, a new mouse study says.Resear ...

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.