Several studies indicated that STF-66247 targets the trans-Golgi network (TGN): brefeldin ... Overall, STF-62247 induces autophagy — a process that has been implicated in a number of diseases ...

ER–Golgi transport: overexpression of LRRK2 may ... the deposition of both α-syn and LRRK2 protein aggregates. Autophagy: the α-syn A53T mutation seems to interfere with the chaperone-mediated ...