First, gram-negative bacteria have a thin cell wall that is about 1.5 to 10 nanometers across, whereas gram-positive bacteria have a thick cell wall measuring about 20 to 80 nanometers.

Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13 ...

Infections by multidrug resistant organisms (MDROs) are a global health threat with a worrying increasing trend. In fragile ...

Purpose. The appropriateness of combination therapy for infections caused by gram-negative organisms is examined. Summary. Mortality from Pseudomonas aeruginosa infection is particularly high ...

Gram-positive cell walls have a thick peptidoglycan layer beyond the plasma membrane. Characteristic polymers called teichoic and lipoteichoic acids stick out above the peptidoglycan and it is because ...

“We identified and developed two small molecules that inhibit a protein in the lipopolysaccharide synthesis pathway in the cell wall of the gram-negative bacteria,” Anders Karlén, one of the ...