Penn researchers have developed a platform that emulates human bone marrow’s native environment. This breakthrough addresses ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

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Bone marrow is made of several main ingredients. These include hematopoietic stem cells (HSCs), which differentiate into the many types of cells in human blood; endothelial cells, which make up ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to ...

In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow’s intricate structure, focusing on leptin receptor-expressing (LepR+ ...

Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.

On January 13, 2025, a study (DOI: 10.1038/s41413-024-00387-9) published in Bone Research introduced a newly optimized imaging protocol designed to visualize LepR + stromal cells within optically ...

Ossium Health, a clinical-stage bioengineering company with a first-of-its-kind bone marrow banking platform for processing ...