Even today, most biophysical spiking models are based on the H-H equations. What have computational neuroscientists learned from Hodgkin and Huxley? First, they chose the right model system.

Models can provide experimentally testable predictions and a level of insight not otherwise achievable. A classic example is the Hodgkin-Huxley model for the generation of axon potentials in the ...

(This concept and velocity equation came from the historic study of action potentials in the squid giant axon by Alan Hodgkin and Andrew Huxley in the 1940s-50s, partly at MBL.) However ...