The hypothalamus consists of several nuclei that ... there are orexigenic coexpressing neuropeptide Y/Agouti gene-related protein (NPY/AgRP) and anorexigenic pro-opiomelanocortin (POMC)/cocaine ...

The hypothalamus integrates neurohormonal signaling from gut and adipose tissue. Specific hypothalamic nuclei, including the dorsomedial nucleus (DMN), paraventricular nucleus (PVN) and ...

Within the arcuate nucleus (ARC) of the hypothalamus, leptin influences two key neuronal populations. One, the agouti-related protein (AGRP) and neuropeptide Y (NPY) neurons, stimulates hunger ...

Confocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant) of a mouse brain. Disclaimer: AAAS and ...

There are also leptin receptors in MCH neurons of the lateral hypothalamus. Genetic and physiological studies have shown that NPY, AgRP, α-melanocyte-stimulating hormone (α-MSH, a POMC-derived ...

AgRP and NPY stimulate appetite, which may help to explain the hyperphagia the authors observed. Much work remains to be done to untangle the network of chemical signals that the hypothalamus ...

Lowell says. Much of his research focuses on agouti-related peptide (AgRP) neurons, nerve cells in the hypothalamus at the base of the brain that are activated by fasting. Lowell’s group, along with ...

To investigate the hypothalamus as a potential key target of 17α-estradiol ... Interestingly, QRFP, IGF1, AGRP, TAC4, GRP, CLU, BNF, PCSK7, PACAP, ANP, TAC3, CRH, INSL6, and PRL displayed significant ...

The hypothalamus in the brain contains the temperature monitoring centre for the body. The hypothalamus receives nerve impulses from structures in the skin called thermoreceptors, which give ...

The researchers demonstrate that an appetite-promoting inflammatory cascade driven by these immune cells occurs within the mediobasal region of the hypothalamus, a structure that, according to a news ...