STUDY OBJECTIVES: To investigate the time of onset and incidence of complications in patients presenting to the emergency department with an IV heroin overdose and the need for routine admission ...

Infuse IV over 10–30 mins ... May reduce absorption of gastric pH-dependent drugs (eg, iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole).

However, heroin use subsided when the synthetic opioid ... said that it has serious concerns about people switching to ...

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Its mechanism of action ... pain as adjunct to opioid analgesics, where an IV route is considered clinically necessary.