肿瘤治疗始终面临着诸多挑战,提高治疗的特异性、疗效并降低副作用是关键目标。免疫疗法作为一种新兴的治疗手段,在过去几十年中得到了广泛研究。嵌合抗原受体 T(CAR-T)细胞疗法在血液系统恶性肿瘤治疗中取得了显著成效,但存在生产成本高昂、制备过程复杂以及潜在慢性毒副作用等问题。
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy by targeting key immune pathways such as PD-1, PD-L1, CTLA-4, and LAG-3 to enhance the immune system's ability to combat ...
Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...
Researchers have developed a groundbreaking AI model that identifies tumor-fighting immune cells, enhancing cancer ...
Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy have developed ...
The following is a summary of “Antibiotics use decreases survival in cutaneous squamous cell carcinoma patients receiving ...
In oncology, immunotherapy stands as a transformative approach for treating solid tumors, notably through pioneering treatments like immune checkpoint ...
Researchers have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.
Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed ...
Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...
All patients involved in the phase 1 trial of a personalized cancer vaccine for high-risk stage III/IV kidney cancer showed a ...