Central nervous system prophylaxis is recommended with the administration of high-dose methotrexate and/or intrathecal injection of chemotherapy in patients with anaplastic large-cell lymphoma (ALCL).

Intrathecal methotrexate 12.5 mg is given on the CO week provided there is no raised intracranial pressure with 15 mg folinic acid until the human chorionic gonadotrophin normalizes. CO ...

Methotrexate 1g/vial; pwd for IV, IM, intra-arterial, or intrathecal administration after dilution; preservative-free. Non-metastatic osteosarcoma in patients who have undergone surgical resection ...

Intrathecal methotrexate 12.5 mg is given on the CO week provided there is no raised intracranial pressure with 15 mg folinic acid until the human chorionic gonadotrophin normalizes. CO ...