Eight years ago, at the age of 53, Jeff Miller woke up, got out of bed and fell to the floor. Although he was having trouble seeing, he managed to get down the stairs to the first floor of his ...

Acute limb ischemia (ALI) results from a sudden obstruction in the arterial flow to the extremity due to an embolism or thrombosis. Embolic problems result in a greater degree of ischemia than ...

Focal cerebral ischemia was induced by occlusion of the right MCA in male C57BL/6 mice (wild-type and ORP150-transgenic mice) weighing between 25–30 g using an intraluminal filament technique ...

Current understanding of microvascular changes in chronic limb-threatening ischemia remains limited, partly because the tissue microvasculature is difficult to study in human patients.